O. Theron Clagett (1908-1990)

Leon Chesley (1908-2000)

Leon Chesley studied hypertension, or high blood pressure, in pregnant women during the mid-twentieth century. Chesley studied preeclampsia and eclampsia, two hypertensive disorders found in approximately five percent of all US pregnancies. In New Jersey and New York, Chesley devoted over forty years to researching preeclampsia and eclampsia, and conducted several long-term studies using the sa...

1908 Scheme I + - CHOC

A synthetic strategy for the preparation of the quinone antibiotic naphthyridinomycin is outlined. An efficient synthesis of key tricyclic intermediate 6 is described. Naphthyridinomycin (I) is an architecturally interesting broad spectrum antibiotic produced by Streptomyces lusitanus. 9 1 2 The structure elucidation of 1 in I974ia,b revealed its unique hexacyclic structure which shared a quino...

Practical Medicine, Series 1908

Dev117903 1893..1908

Malformation of the urogenital tract represents a considerable paediatric burden, with many defects affecting the lower urinary tract (LUT), genital tubercle and associated structures. Understanding the molecular basis of such defects frequently draws on murine models. However, human anatomical terms do not always superimpose on the mouse, and the lack of accurate and standardised nomenclature ...

Split-thickness skin-grafting the post-Clagett pleurostomy cavity.

' 2004 Canadian Medical Association A the surgical complications of pulmonary resections and pneumonectomies, bronchopleural fistulae (BPF) persists as the gravest complication for the thoracic surgeon. BPF can prolong hospital stay and increase mortality to a rate of 50%. Its management is challenging and controversial. We report our recent experience with empyema and late BPF in a patient aft...